Wise Dan, who paid $2.80 on a $2 win bet, won the Fourstardave for the second consecutive year.
McNeill and his wife placed the $15,000 wager using money provided by Marylou Whitney and John Hendrickson, as part of the Saratoga 150 celebration.
The couple is expecting their first child in September and plans to use the windfall to start a college education fund.